Pre-incisional epidural magnesium provides pre-emptive and preventive analgesia in patients undergoing abdominal hysterectomy

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Pre-incisional epidural magnesium provides pre-emptive and preventive analgesia in patients undergoing abdominal hysterectomy.

BACKGROUND This prospective, randomized, double-blind study was designed to evaluate the preemptive and preventive analgesic efficacy of adding magnesium to a multimodal regimen of patient-controlled epidural analgesia (PCEA) in patients undergoing abdominal hysterectomy. METHODS Ninety patients were randomly assigned to one of the three groups. Pre-magnesium patients received bolus of magnes...

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Pre-emptive effect of epidural sufentanil in abdominal hysterectomy.

BACKGROUND Experimental studies suggest pre-emptive administration of analgesics is effective but clinical evidence is less convincing. METHODS Forty-one patients undergoing abdominal hysterectomy were allocated randomly in a double-blind fashion to receive sufentanil 50 micrograms via a lumbar epidural catheter before or at the end of surgery. RESULTS Sufentanil consumption from a patient-...

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CLINICAL PRACTICE Pre-incisional epidural ropivacaine, sufentanil, clonidine, and (S)1-ketamine does not provide pre-emptive analgesia in patients undergoing major pancreatic surgery

Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, Knappschaftskrankenhaus Bochum Langendreer, University Hospital Bochum, In der Schornau 23-25, 44892 Bochum, Germany. Department of Anaesthesiology, Department of Surgery, and Pharmacy, University Hospital Hamburg Eppendorf, Hamburg, Germany. Department of Anaesthesiology and Critical Care Medicine, Academic Hospital Solin...

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Pre-emptive analgesia.

Transmission of pain signals evoked by tissue damage leads to sensitization of the peripheral and central pain pathways. Pre-emptive analgesia is a treatment that is initiated before the surgical procedure in order to reduce this sensitization. Owing to this 'protective' effect on the nociceptive system, pre-emptive analgesia has the potential to be more effective than a similar analgesic treat...

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Pre - Emptive Extradural Analgesia

5. Mallett SV, RoUes K, Cox D, Burroughs A, Hunt B. Intraopcrative use of aprotinin (Trasylol) in orthotopic liver transplantation. Transplantation Proceedings 1991; 23: 19311932. 6. Thomson JF, Roath OS, Francis JL, Webster JHM, Chant ADB. Aprotinin in peripheral vascular surgery. Lancet 1990; 335:911. 7. Kobrinsky NL, Letts MR, Patcl LR, l-Desamino-8-D arginine vasopressine (Desmopressin) dec...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2008

ISSN: 0007-0912

DOI: 10.1093/bja/aen274